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The Lancet Psychiatry, 13 (4), 327335

[55] Semaglutide acts on these alterations by mitigating adipocyte hypertrophy and limiting excessive lipid storage through the downregulation of lipogenic enzymes such as lipoprotein lipase (LPL) and ANGPTL4

Moreover, in a clinical observation, a 2-year case study was carried out on a 72-year-old man with type-2 diabetes, stage 34 chronic kidney disease, and congestive heart failure