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Its not driven by a single failure, but by gradual shifts across interconnected systems cellular energy, oxidative balance, immune tone, and tissue integrity each influencing the others over time

10.1111/j.1528-1157.2000.tb02170.x Epilepsia 13 DodickD

Increased iHSP72 expression in hepatocytes prevents steatosis and liver injury, underscoring its role in preserving hepatic metabolic homeostasis

Although probiotic supplementation shows promising potential in improving thyroid function in thyroid diseases, further human studies on the effects of probiotics as adjuvant therapy for thyroid diseases are required ( Table 1 )

System xc is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice