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Cardiovascular outcome trials (CVOTs) of GLP-1RAs To date, the REWIND study has demonstrated for the first time that primary cardiovascular prevention strategies can significantly reduce cardiovascular adverse events in patients with T2DM, regardless of whether or not these patients are co-diagnosed with CVD [23]

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Since then, two GLP1 RAs requiring only once-daily injection have become available, followed by three which require only once-weekly injection (Figure 1)

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Understanding these distinctions is essential for timely recognition and intervention, ultimately improving patient outcomes in acute cardiac events