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534,535 Resting membrane of aged astrocytes remains highly hyperpolarised (~80 mV), the input resistance increases somewhat with age, thus reflecting morphological shrinkage

However, even the most specific inhibitor can have effects beyond the therapeutic target, i.e., off-target effects, which may significantly affect the outcome

It is a tripeptide composed of three amino acids cysteine, glutamic acid, and glycine

One retrospective study demonstrated that patients treated with 0.3% tacrolimus were significantly more likely to stabilize in 3 months compared with patients treated with clobetasol/betamethasone

It may occur sporadically, for example after an insect bite, or persist in a chronic context, such as in the case of eczema