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Deficiencies or imbalances can exacerbate symptoms such as pain, inflammation, bloating, and fatigue

This body of evidence provides a mechanistic rationale for advancing GLP-1R agonists as candidate pharmacotherapies for AUD, with relevance for individuals characterized by specific genetic profiles, nicotine co-use, or metabolic vulnerability

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Why GLP-1 Medications Are Prescribed GLP-1 receptor agonists such as semaglutide (Wegovy) and liraglutide are approved for: Adults with a body mass index (BMI) of 30 or greater Adults with a BMI of 27 or greater with at least one weight-related condition such as hypertension, type 2 diabetes, or high cholesterol These medications mimic the GLP-1 hormone, which helps regulate appetite, glucose levels, and insulin secretion