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Stopping treatment prematurely prevents achieving maximum potential results

While this represents a smaller percentage than some diet-only approaches, it still constitutes significant muscle loss for those losing substantial amounts of weight

For a deeper look at the mechanism behind this effect, our guide on how GLP-1 delays gastric emptying is a helpful companion read

Here, we have compared the glucagonostatic effects of GLP-1(736) and (936) in vitro using physiological (pmol/l) concentrations of the peptides and over a wider range of glucose concentrations in isolated mouse and human islets (some from donors with type 2 diabetes) and extend these data to the in vivo situation with a particular focus on the counterregulatory increase in plasma glucagon during insulin-induced hypoglycaemia