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Mathematical and microbiological evidence of negligible contamination A 2022 study mapping skin microflora and modeling needleskin interactions found that the probability of actually carrying live bacteria below the skin during a subcutaneous injection is effectively zeroand no clinical skin infections have ever been documented under these conditions (PMC)

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Some researchers continue indefinitely, while others cycle off after reaching their weight loss goals

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American journal of clinical dermatology 2003;4(10):661-67 [PubMed: 14507228] 127