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The final aim of our study was to unravel metabolic vulnerabilities and biomarkers that may be used in the clinical setting

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It found that in participants with overweight or obesity (body mass index (BMI) 27 kg/m 2 ), once-weekly injections of 5 mg, 10 mg or 15 mg of tirzepatide led to mean weight reductions of 15%, 19.5% and 20.9%, respectively, compared to placebo

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