Two regulatory bodies are relevant here: The Medicines and Healthcare products Regulatory Agency (MHRA) oversees the regulation of herbal medicines through the Traditional Herbal Registration (THR) scheme
The aggregation of these peptides into oligomers and their subsequent deposition as extracellular senile plaques is facilitated by interactions with apolipoproteins and proteoglycans, contributing to the synaptic dysfunction and neurodegeneration that define the disease ( Additionally, the hyperphosphorylation of tau protein disrupts its binding to neuronal microtubules
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