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However, in patients with MPNST, R0 resection is not always possible due to the nature and biology of these tumors

Roy et al., 2023), since A aggregation has been determined as source of oxidative stress (Karapetyan et al., 2022) and oxidative stress has been shown to increase the aggregation of A (Mandal et al., 2022)

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For those who are seasoned NAD+ users, or that are administering higher doses (more than 50 units weekly), we recommend ordering a 5mL vial to support a full monthly supply