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10.1530/eje.0.1400577 Eur

202,203 Essentially, the imported disulphide-containing proteins undergo cathepsin-catalysed degradation in the lysosome, leading to the formation of cystine, which is then effluxed by the cystinosin transporter into the cytosol, where it is reduced to cysteine in a process that requires NADPH, leading to the formation of oxidised glutathione

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A mild gradual cognitive decline is expected when we age, but considerable change may mean something else is happening with the brain

Caffeine and other adenosine receptor antagonists attenuate dopaminergic neurotoxicity in a mouse model of PD, suggesting such molecules have neuroprotective effects [52]