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Additionally, GLP-1RAs are recommended for patients with T2DM and chronic kidney disease, and individuals with a history of cardiovascular disease or myocardial infarction may also benefit from GLP-1RAs

doi: 10.1038/oby.2006.300 122 RehfeldJF

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She points to a study in which two groups of participants followed a hypocaloric dietconsuming fewer calories than the body burns throughout the daybut only one of the groups drank 500 ml of water before each daily meal

So while appetite is lower, the medication itself doesnt teach someone how to structure their meals, prioritize protein or fuel their training, and thats where some of the more interesting patterns start to show up