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NEJM , Hurtado, Maria D., et al

Hilbert, A., Hoek, H

Its important for those with pre-existing gastrointestinal conditions

However Lillys demonstration that a GIP/GLP-1 receptor co-agonist (tirzepatide) has superior efficacy compared to selective GLP-1 receptor agonists, has renewed interest in the first incretin. Lilly rolled out their SURPASS trials to position their agent amongst existing diabetes medications and GLP-1 agonists