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We stated in the correction notice to the CY 2026 PFS proposed rule that we would use the MEI update based on historical data through the second quarter of 2025 to determine the final MEI percentage increase and the CY 2026 KX modifier threshold amounts in the CY 2026 PFS final rule

FOXO4-DRI mainly kills senescent cells because these cells depend on a specific FOXO4-p53 connection to stay alive