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In addition, most of the major cardiovascular and kidney outcome trials have been conducted in global populations, with relatively limited representation from Indian patients
Exon Duplication and Divergence in the Human Preproglucagon Gene
FDA has underlined the adverse effects of DPP-IV inhibitor drugs such as Januvia, Janumet, Janumet XR, Onglyza, Kombiglyze XR, Tradjenta, Glyxambi, Jentadueto, Nesina, Kazano, and Oseni with active compounds sitagliptin, sitagliptin and metformin, sitagliptin and metformin extended release, saxagliptin, saxagliptin and metformin extended release, linagliptin, linagliptin and empagliflozin, linagliptin and metformin, alogliptin, alogliptin and metformin andalogliptin, and pioglitazone, respectively (60)
Nevertheless, the potential beneficial secondary CV effects are the subject of intense interest
