The drugs, typically taken once weekly as injections, work by helping the pancreas increase the production of insulin to move sugar from the blood into body tissues
Semaglutide is taken once a week, while liraglutide is a daily injection
It is important to work with a healthcare provider to determine which treatment is best for you
However, a contradicting study revealed that patients with a BMI below 35 experienced a significant reduction in cardiovascular events, whereas those with a BMI of 35 or higher did not, indicating a potential correlation
Comparisons Of Efficacy And Safety Of Oral Semaglutide And Injectable Liraglutide Or Semaglutide To determine efficacy and safety of oral semaglutide as monotherapy, the 26-week, phase 3, double-blinded, placebo-controlled RCT (PIONEER-1) primarily aimed to demonstrate glycemic superiority of once-daily oral semaglutide against placebo in 703 T2D adults with mean age of 5511 years, BMI of 31.86.6 kg/m 2 , baseline HbA1c of 8.00.7% (638 mmol/mol), and diabetes duration of 3.5 years