Relative ratios of pyruvate to citrate metabolite levels of each indicated cell line from the metabolomics analysis in Figure 4E
As confirmed by the aforementioned results, ferroptosis plays an important role in TBI (Xie et al., 2019)
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In aged WT versus Mda5 -/- regions we found CTCF (CCCTC-binding factor, 1e-911), ETV2 (Ets variant 2, 1e-248), ERG (ETS transcription factor ERG, 1e-232), IRF3 (1e-21), PU1 (1e-133), JUN-AP1(1e-72) in the reduced regions and CTCF (1e-139), ETV2 (1e-69), ETS1 (1e-55), PU1 (1-36), RUNX (1e-31), IRF3 (1e-05) in the induced regions (Fig
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