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Relative ratios of pyruvate to citrate metabolite levels of each indicated cell line from the metabolomics analysis in Figure 4E

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As confirmed by the aforementioned results, ferroptosis plays an important role in TBI (Xie et al., 2019)

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In aged WT versus Mda5 -/- regions we found CTCF (CCCTC-binding factor, 1e-911), ETV2 (Ets variant 2, 1e-248), ERG (ETS transcription factor ERG, 1e-232), IRF3 (1e-21), PU1 (1e-133), JUN-AP1(1e-72) in the reduced regions and CTCF (1e-139), ETV2 (1e-69), ETS1 (1e-55), PU1 (1-36), RUNX (1e-31), IRF3 (1e-05) in the induced regions (Fig

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