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No receptor-mediated adverse events (e.g., cardiovascular effects, endocrine disruption) have been reported, consistent with NNMT's limited expression outside metabolic tissues

This may point to the receptor for IL-1, IL-1R1, as a viable therapeutic target for reducing BBB damage after ischemic reperfusion injury (Pan et al., 2023)

But, in my view, all those will be to little to late

Today, the high prices and periodic shortages often observed with GLP-1R agonists limit equitable access, underscoring the importance of policy action, stable manufacturing, and fair distribution

But, many have found out the hard way that when they stop taking the drug, their appetite comes roaring back