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Research published in JCI Insight describes tirzepatide as an "imbalanced and biased" dual agonist, meaning it shows equal affinity for the GIP receptor compared to native GIP but approximately 5-fold weaker affinity for the GLP-1 receptor compared to native GLP-1

Preclinical data only

Unlike certain weight management treatments that target hunger signals and satiety hormones, BPC-157 does not appear to significantly affect appetite regulation

Protocols commonly use 200500 mcg subcutaneously, once or twice daily, in 46 week cycles, but there is no FDA-approved product or official dosing

That's why I've developed six non-negotiable rules for responsible peptide use around surgery