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A search of the FDA Adverse Event Reporting System (FAERS) database identified 20 cases of acidosis reported as diabetic ketoacidosis (DKA), ketoacidosis, or ketosis in patients treated with SGLT2 inhibitors from March 2013 to June 6, 2014 (see Data Summary)

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Medical and Lifestyle Factors That Increase Risk Obesity is a major risk factor, as a higher body weight is associated with increased cholesterol in the bile