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In addition, when canola plants were treated with biochar alone or in conjunction with microbial inoculation, antioxidant enzymes increased significantly

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Excessive generation of ROS within ovarian, adipose, and hepatic tissues overpowers antioxidant defenses, leading to oxidative damage of lipids, proteins, and mitochondrial DNA ( Androgen excess exacerbates redox disequilibrium by promoting NADPH oxidase activity and mitochondrial ROS production, while simultaneously impairing follicular maturation and oocyte quality ( Figure 1 represents the involvement of redox imbalance and endocrine dysregulation in the ovary, leading to hyperandrogenism or PCOS

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