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Alloxan hepatic metabolism may have been responsible for the increase in ALT/AST levels in diabetic animals, since the structural similarity with the glucose molecule allows its absorption by the cell through the GLUT2 transporter 38 , occasioning possible damage to cells which express this carrier

We are proud of the pipeline that we have built in obesity and diabetes and the strong data we have generated to date, stated Heather Turner, JD, Carmots CEO

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3,28 The combined activation of GLP-1 and GIP receptors more effectively reduces glucose levels and stimulates weight loss compared to the placebo, semaglutide and dulaglutide, or insulin