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This detoxification process is essential for cellular health and metabolic efficiency
(Hammer Nutrition Direct, 2019)
However, when mitochondria become damaged or depolarized due to oxidative stress or high glucose levels in DR, PINK1 accumulates on the outer mitochondrial membrane
GLP-1 (Glucagon-Like Peptide-1) is primarily produced in enteroendocrine L-cells located in the distal small intestine (ileum) and colon in response to eating
En un pronunciamiento conjunto publicado el 11 de agosto del 2023, la American Gastroenterology Association (AGA), la American Association for Study of Liver Disease (AASLD), el American College of Gastroenterology (ACG), la American Society of Gastrointestinal Endoscopy (ASGE) y la North American Society For Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) reconocieron que los agonistas del GLP-1 usados para la diabetes y la prdida de peso pueden alterar el vaciamiento gstrico, y si bien esto puede generar preocupacin sobre la seguridad para realizar procedimientos endoscpicos con sedacin por el riesgo de aspiracin, la asociacin an es anecdtica y el riesgo de gastroparesia se considera dosis dependiente
