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Since computational chemistry can save time, funds and animal sacrifice compared to the traditional experiments, the quantitative structureactivity relationship (QSAR) approach may also be used for NP toxicity prediction

eNOS, endothelial nitric oxide synthase

A review of medicinal plants with renoprotective activity in diabetic nephropathy animal models

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However, a review of recent studies indicates that this is soon to change as more clinicians become aware of the unique advantages of nasal delivery of peptides and other therapeutics