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Verhoef P, Stampfer MJ, Buring JE, Gaziano JM, Allen RH, Stabler SP, Reynolds RD, Kok FJ, Hennekens CH, and Willett WC (1996)
Most prominently, the substantial reduction in total and visceral adiposity is tightly linked to improved insulin sensitivitya core pathophysiological determinant of MASLD
A more accurate assessment of these values was not possible due to low solubility of these compounds at high micromolar concentrations
But the indication for the drug isn't BMI of 30 and has tried a bunch of other stuff
The cellular complexity of skin tissue and the sparse distribution of HFSCs likely explain this result
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