AP GLP-1 signaling is necessary and sufficient for producing taste avoidance following peripheral GLP-1RA administration, suggested by Zhang and colleagues recently
doi:10.1093/nutrit/nuv065 Prado, C
CKD chronic kidney disease, CV cardiovascular, CVD cardiovascular disease, HFrEF heart failure with reduced ejection fraction, EF ejection fraction, KCCQ-CSS Kansas City Cardiomyopathy Questionnaire Clinical Summary Score, ABI ankle-brachial index, TBI toe-brachial index, BMI body mass index, NYHA New York Heart Association functional classification, NT-proBNP N-terminal pro-B-type natriuretic peptide, MA meta-analysis, MACE major adverse cardiovascular events, T2DM type 2 diabetes mellitus Table 2
Gastric stasis in neuronal nitric oxide synthase-deficient knockout mice
However, it's worth noting that the delayed gastric emptying effect may affect the absorption of some oral medications, particularly those with a narrow therapeutic index, which may require monitoring