In the rat model of neuropathic pain induced by CCI, Fer-1 upregulates GPX4 expression, downregulates ACSL4 expression, and decreases the content of iron in the spinal cord, while erastin has the opposite effect
Nat Med 23(11):13621368 Saha SK, Islam SMR, Abdullah-Al-Wadud M, Islam S, Ali F, Park KS (2019) Multiomics analysis reveals that GLS and GLS2 differentially modulate the clinical outcomes of cancer
This review provides an up-to-date and integrative overview of current evidence regarding ASTs mechanisms of action across experimental and preclinical models of neurodegenerative diseases such as Alzheimers, Parkinsons, and Huntingtons diseases
Minimal Side Effects & High Safety Profile Compared to many pharmaceuticals, peptide therapy has virtually no known side effects
Xie, K., Sun, Y., Li, X., Yang, S., Wang, M