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Arch Toxicol 94(3):651715

Side effects Commonly reported side effects include: Nausea Constipation Diarrhea Vomiting Stomach (abdominal) pain Indigestion Headache Other potential side effects: Fatigue Belching Heartburn Bloating Hair loss Decreased appetite Gastroesophageal reflux disease Injection site reactions Most GI side effects are more common in the first few weeks and tend to ease as your body adjusts

Pentoxifylline ameliorates subclinical atherosclerosis progression in patients with type 2 diabetes and chronic kidney disease: a randomized pilot trial

Appl Physiol Nutr Metab 2016

Another study reports that a significant loss of parvalbumin and somatostatin inhibitory neurons in the ventral hippocampus, which results in excitation/inhibition (E/I) imbalance, leads to anxiety-like behavior (Li et al., 2022)