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Several L-asparaginase preparations have been approved by the European Commission or the Food and Drug Administration (FDA), primarily for the treatment of hematologic malignancies like acute lymphoblastic leukemia (ALL) [119, 120]

Whereas, with placebo treatment, retinopathy continued to progress as the visual acuity was reduced by 3.2% (left) and 7.5% (right), assessed by the Snellen Chart

Modules exhibiting condition-associated shifts in module eigengene expression captured co-regulated genes, whose expression changes paralleled those observed for selected LR components

76 : 228239 Rudolphi KA, Schubert P, Parkinson FE, Fredholm BB

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