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Stomach acid and digestive enzymes can break it down, meaning only a fraction of the vitamin may actually enter your bloodstream

On the question of raw, proven efficacy for photoaging, the honest answer is that tretinoin has the stronger evidence base but the picture is more nuanced than a simple winner-takes-all verdict

For patients, that means fewer options when a commercial drug is unavailable, discontinued, or wrong for their needs

You can, but only if you plan to use the entire contents of the vial in a single session