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doi: 10.1016/j.plaphy.2009.03.001

The study investigated the relationship between protein concentration and the accuracy of the current method

GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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This seemingly small chemical modification brings profound functional changes: the acetylated thiol group is protected from oxidation and enzymatic breakdown, while the overall molecules lipophilicity is significantly enhanced, allowing it to cross biological membranes more easily