For example, Zepbound and Mounjaro contain both GLP-1 and tirzepatide, which is a glucose-dependent insulinotropic polypeptide (GIP) receptor
[4] The most exhaustive empirical research on dieting supports this claim
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We will then go through the mechanism of GLP-1 acting on neural circuits within the CNS that regulate satiation and satiety, particularly focusing on regulation by the hypothalamus
Considering the previously discussed information, GLP-1 analogues, by interacting with key structures within the reward circuitrysuch as the mesolimbic and corticolimbicstriatal systemsmay influence the distinct phases of the addiction cycle, including intoxication, withdrawal, and anticipation/craving [41]