Treatment assignment: emulation of randomization by propensity score-based overlap weighting To balance baseline characteristics between GLP-1RA initiators and noninitiators, we applied propensity score-based overlap weighting, which emphasizes the population with clinical equipoise 28
Melatonin: a versatile protector against oxidative dna damage
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however, these drugs have been misused Currently available data do not suggest that rhGH treatment should be used to promote longevity Lack of GH action in mouse models is associated with extended longevity, but the mechanism underlying the increased lifespan has yet to be established Given the effects of reduced GH/IGF-1 signalling on lifespan in rodents, decreased GH action might be beneficial for humans, but clinical trials are needed to assess long-term outcome of GH/IGF-1 inhibition This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 186,36 per year only 15,53 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF