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For instance, hypertriglyceridemia was induced under high-fat diet conditions and then cerulein was then injected to establish hypertriglyceridemic pancreatitis (HTGP) models

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Specifically, the ROS scavenger butylated hydroxyanisole delayed TNF-induced necroptosis but had no effect on necroptosis induced by direct RIPK3 oligomerization, suggesting that ROS may facilitate upstream signaling events rather than serve as an obligate execution mechanism 80

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