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GLP-1 acts through its receptor, GLP-1R, which is a class B G-protein-coupled receptor (GPCR)

However, clinical evidence remains mixed, and weight loss achieved through GLP-1 therapy often improves GERD symptoms

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Research also shows that inositol is a simple and safe treatment that is capable of improving reproductive axis functioning in PCOS patients, reducing the hyperinsulinemic state that affects LH secretion and restoring spontaneous ovarian activity and consequently clinical pregnancy rate