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Enoxaparin treatment administered at both early and late stages of amyloid beta deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain Abeta levels

A compelling theory posits that ACEs may influence iron metabolism, potentially resulting in iron shortage and IL-6 signaling, which are linked to neurodevelopmental consequences [200], and an amplified amygdalar response to emotionally unfavorable stimuli and a reduced amount of hippocampal gray matter [201]

doi: 10.1016/j.cell.2013.10.019

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