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Managing Efficacy and Side Effects Throughout the Week Because GLP-1 concentration peaks early in the week and gradually declines, many patients notice stronger appetite suppression on days 1 through 4 after injection, with a gentler effect by days 6 and 7

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Mild pain and swelling at the injection site can be eased by applying an ice pack for 1020 minutes as needed/when necessary

Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women