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Meanwhile, 25-OHC markedly upregulated cytochrome b5 reductase 1 (CYB5R1) and POR, suppressed GSH expression, and promoted lipid peroxidation, thereby enhancing the sensitivity of IMS32 cells to ferroptosis and aggravating neuroglial injury

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[DOI] [PubMed] [Google Scholar] 63.Vella A, Shah P, Reed AS, Adkins AS, Basu R, Rizza RA

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Subsequently, we decided to reduce the FBS concentration to 1%, resulting in significant differences under this condition