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To participate in the model, state Medicaid programs must sign a State Agreement with CMS and then adopt supplemental rebate agreements (SRAs) with each participating manufacturer that reflects the standard key terms that the participating manufacturers and CMS have agreed to

This approach is especially valuable for patients whose genetic test results indicate heightened GLP1R sensitivity or those with a history of digestive issues

There has been modeling done to explore alternative dosing regimens of GLP-1s that simultaneously reduce costs and maintain weight-loss efficacy, but theres limited evidence and no formal guidelines to support this practice, Zimmermann says

Ultimately, the cycle of innovation that once centered around the hospital is now extending beyond its walls

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