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As mentioned above, ferroptosis could be induced to exert anti-tumor functions via signaling pathway modulation, non-coding RNA expression, DNA methylation, histone modification, CSCs, microenvironment remodeling, and so on

Funding This work was supported by the National Natural Sciences Foundation of China (No

Some studies suggest that lactate is a more efficient energy substrate than glucose, with evidence indicating that neurons generate energy more effectively when utilizing lactate (Dienel 2019)