Crockett Chair in Diabetes Research, medical director of AdventHealth Diabetes Institute and a Healio | Endocrine Today Co-editor, described the FLOW findings as practice changing. Pratley said while the American Diabetes Association Standards of Care recommends SGLT2 inhibitors as the first-line treatment for most adults with type 2 diabetes and CKD, the FLOW trial may change that in the future
That said, weight gain can still occur after liposuction, especially if those who use it continue their unhealthy eating habits
It is a reasonable precaution in the absence of evidence either way
It standardizes study design, PK parameters, and BE acceptance criteria across ICH regions (US, EU, Japan, Canada)
Additionally, it has demonstrated anti-inflammatory properties, potentially benefiting joint health and overall well-being