Ask questions about expected outcomes, monitoring requirements, and alternative weight loss strategies to make an informed choice that aligns with your wellness priorities
is supported by the National Institutes of Health grants R01AG059008, R01AG073212 and P30AG072980, as well as by the Barrow Neurological Foundation
Jennifer Hardy Sep 20, 2025 7 min read I keep seeing questions about frozen semaglutide and frozen tirzepatide, usually after someone makes a mistake like leaving it in the car or accidentally putting it in the freezer
Individuals with type 1 diabetes, thyroid cancer, multiple endocrine neoplasia, or end stage kidney disease at any time until cohort entry or individuals with dialysis or the latest eGFR 70 years, by males versus females, by insulin use, by atherosclerotic cardiovascular disease (i.e., myocardial infraction, angina, coronary artery disease, coronary revascularization, peripheral artery disease, aortic atherosclerotic disease, or cerebrovascular disease), by renal insufficiency (i.e., chronic kidney disease or the latest eGFR 70 years (HR [95% CI]: 0.95 [0.831.08])
Furthermore, cagrilintide 2.4 and 4.5 mg reduced triglycerides and very-low-density cholesterol significantly more than pooled placebo, with similar reductions as seen with liraglutide 3.0 mg
