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& Umek, R
doi:10.3390/nu11050951 Note: Originally published in May 2015, this article has been revised and updated for accuracy and thoroughness.
Furthermore, in line with the beneficial effects of RAS blockers, researchers have also shown that the administration of empagliflozin, a SGLT2i, reduced the expression of IL-6, CCL2, and NF-B in the kidneys of diabetic Akita mice, as well as in cultured kidney tubular cells exposed to high glucose (152, 159)
Andersen A, Lund A, Knop FK, Vilsbll T (2018) Glucagon-like peptide 1 in health and disease
18 UC is characterized by ulceration of the intestinal mucosal layer in the rectum and colon, which in turn affects the entire colon, resulting in dysregulation of intestinal immune factors and disruption of the structure and function of the intestinal barrier
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