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Published clinical trials used continuous daily administration for 12-24 weeks without scheduled breaks, establishing this as a viable approach with maintained safety throughout the treatment period

It is interesting to note that in contrast to most other metal-binding MerRs the [2Fe-2S] clusters are completely solvent exposed, 305 a finding consistent with a role in cellular monitoring of small redox-active compounds

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A functional and structural basis for TCR cross-reactivity in multiple sclerosis