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14 Increasing flux through the MAS, citric acid cycle, or fatty acid beta-oxidation could blunt the aging-induced oxidative shift in the mitochondrial [NAD + ]/[NADH] to slow tissue aging The combined activities of the citric acid cycle, MAS, and fatty acid beta-oxidation that generate mitochondrial NADH appear to decline to a greater extent with aging than the activity of NADH-consuming ETC complex I in neurons, leading to an oxidized mitochondrial [NAD + ]/[NADH] in aged neurons (Dong et al., 2019a)

Cell culture GBM cell lines U118-MG, GA-MG, LN-18, and GL261 were cultured in Dulbeccos Modified Eagle Medium (DMEM) supplemented with 10% fetal bovine serum (FBS) and maintained at 37 C and 5% CO 2

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Nayan Patel: No, they actually, the two professors at the university, so I also teach at Western University School of Pharmacy over there, and in there, they were asking me, what do I do