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The interaction between multiple immunopathological and neuropathological mechanisms in mice with experimental autoimmune encephalomyelitis (EAE), an animal model of MS, results in key pathological features that approximate MS: inflammation, demyelination, axonal loss, and gliosis (81)

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Of more than a hundred compounds measured in the bloodstreams of thousands of individuals, the one most associated with the lowest rates of disease and death was ergothioneine

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