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Signs and symptoms of multisystem inflammatory syndrome in children (MIS-C) include those below - Fever that lasts more than 3 days Vomiting, diarrhea and stomach pain are particularly common and prominent Skin rash Conjunctivitis - red eyes Mucous membrane involvement - Redness or swelling of the lips and tongue Headache, dizziness, or lightheadedness Rapid breathing Sore throat Body pain Redness or swelling of the hands or feet Enlarged lymph nodes Emergency warning signs of MIS-C Severe stomach pain Difficulty breathing Pale, gray or blue-colored skin, lips or nail beds Inability to wake up or stay awake Diagnosis of Multisystem Inflammatory Syndrome Doctors may want to do tests such as blood tests, or imaging tests of the chest, heart or abdomen to check for areas of inflammation and other signs of MIS-C

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Low Zn levels are associated with activation of Caspase-3 and downregulation of the ERK pathway, reduced Ki67-positive cells, increased TUNEL-labeled cells in the subgranular zone (SGZ), arrest of the cell cycle in the G0 G1 phase, promotion of apoptosis in neurons, and modification of cell signals that control the pro-survival and pro-apoptotic gene expression, such as NF- and p53 (189)

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