Clinical studies suggest Se may have potential in mitigating cognitive decline (111,134)
"The natural antioxidant defenses in our body decline as we age, which leads to increased oxidative stress that causes melanocytes to be impaired and produce less melanin, contributing to the loss of hair pigment," Wizemann explains."A lack of antioxidant-rich foods, regular exercise and sleep as well as smoking, excessive stress and alcohol consumption all increase oxidative stress." Deficiencies in vitamins and minerals
Glutathione peroxidase: a selenoenzyme
Finally, pernicious anemia is an autoimmune disease that affects B12 absorption and can result in a deficiency of this vital nutrient
Moreover, it is conceivable, if not likely, that the localization of TBC1D9B is subject to regulation, for example by altering nutrient supply as suggested by our findings in starved cells (see Fig