Medium term
[DOI] [PubMed] [Google Scholar] 148.Hirano T., Mori Y
GLP-1 slows down how quickly food leaves the stomach, helping a person feel full longer and reducing appetite
Aggarwal V, Tuli HS, Varol A, Thakral F, Yerer MB, Sak K, Varol M, Jain A, Khan MdA, Sethi G
Week 48 Typical Outcomes Excellent Responders (Top 25%) Weight loss: 27-31% (59-68 pounds for 220-pound starter) Characteristics: Perfect adherence, implemented all protocols, resistance training consistent, high protein intake maintained Good Responders (Middle 50%) Weight loss: 21-27% (46-59 pounds for 220-pound starter) Characteristics: Good adherence with occasional lapses, followed core protocols, moderate activity Modest Responders (Bottom 25%) Weight loss: 16-21% (35-46 pounds for 220-pound starter) Characteristics: Variable adherence, minimal dietary modification, limited activity, or metabolic resistance factors What Happens After Week 48