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For context, in one study of 175 people with overweight or obesity, participants taking semaglutide: Lost an average of 15 pounds (about 6% of their body weight) within three months Lost an average of 27 pounds (about 11% of their body weight) after six months Recommended lifestyle changes during GLP-1 therapy GLP-1 medications can boost weight loss by increasing satiety and reducing food cravings

The standard reconstitution protocol calls for directing the diluent gently down the side of the vial, allowing it to contact the lyophilized cake gradually rather than blasting it with a direct stream

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